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Pernicious anemia occurs more commonly in people who already have diseases that are linked to immune-system abnormalities, such as Graves disease, hypothyroidism (under-functioning thyroid gland), thyroiditis (inflammation of the thyroid), vitiligo, and Addison's disease (adrenocortical insufficiency)
If you simultaneously reduce dose, change injection timing, and switch sources, you will not know which change helped
B12 injections can be particularly beneficial for those who: Follow a vegan or vegetarian diet Have digestive conditions like Crohns disease or celiac disease Experience chronic fatigue or anaemia Are over the age of 50 Are pregnant or planning to conceive How Often Should You Get a B12 Shot
Verify you are using the correct syringe markings
PubMed Xiong, Y., Mahmood, A., Lu, D., Qu, C., Goussev, A., Schallert, T., & Chopp, M